Cyclic substituted fused pyrrolocarbazoles and isoindolones

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) A61K 31/407 (2006.01) A61K 31/501 (2006.01) A61P 27/02 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2359772

The present invention is directed to cyclic substituted fused pyrrolocarbazoles and isoindolones having formula (I). The invention also is directed to methods for making and using the cyclic substituted fused pyrrolocarbazoles and isoindolones. The compounds are useful as agents for the regulation of protein kinase.

La présente invention concerne des pyrrolo-carbazoles et des iso-indolones cycliques substitués condensés de formule I. Cette invention concerne également des méthodes de préparation et d'utilisation de ces pyrrolo-carbazoles et iso-indolones cycliques substitués condensés, lesquels sont utilisés comme agents de régulation de la protéine kinase.

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