C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 453/02 (2006.01) A61K 31/439 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2493245
This invention relates to novel quinuclidine derivatives and their use as pharmaceuticals. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
La présente invention concerne de nouveaux dérivés quinuclidiniques et leur utilisation comme produits pharmaceutiques. En raison de leur profil pharmacologique, les composés de l'invention conviennent pour le traitement de maladies ou de troubles tels que ceux en relation avec le système cholinergique du système nerveux central, du système nerveux périphérique, de maladies et de troubles en relation avec la contraction des muscles lisses, de maladies et de troubles endocriniens, de maladies et de troubles en relation avec la neuro-dégénérescence, de maladies et de troubles en relation avec l'inflammation, la douleur, et les symptômes de sevrage provoqués par l'arrêt de la consommation abusive de substances chimiques.
Ahring Philip K.
Jorgensen Tino Dyhring
Nielsen Elsebet Ostergaard
Olsen Gunnar M.
Peters Dan
Mccarthy Tetrault Llp
Neurosearch A/s
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