Treatment of amyloid- and epileptogenesis-associated diseases

Details Treatment of amyloid- and epileptogenesis-associated diseases Treatment of amyloid- and epileptogenesis-associated diseases

C - Chemistry, Metallurgy

07

C

C07C 309/24 (2006.01) A61K 31/185 (2006.01) A61K 31/381 (2006.01) A61K 31/4164 (2006.01) A61K 31/42 (2006.01) A61K 31/425 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61P 25/00 (2006.01) C07D 209/14 (2006.01) C07D 213/38 (2006.01) C07D 233/20 (2006.01) C07D 239/06 (2006.01) C07D 263/10 (2006.01) C07D 265/08 (2006.01) C07D 277/10 (2006.01) C07D 279/06 (2006.01) C07D 317/58 (2006.01) C07D 333/02 (2006.01) C07D 333/50 (2006.01)

Patent

CA 2556706

Methods of treating or preventing an amyloid-related disease in a subject by administering to a subject a therapeutic amount of a compound of the invention are described. Also included are methods for inhibiting epileptogenesis in a subject, by administering to a subject an effective amount of an anti- epileptogenic agent. Methods for treating a subject suffering from an epileptogenesis-associated condition, by administering to the subject an effective amount of an anti-epileptogenic agent are also included. Methods for treating convulsions in a subject by administering to the subject an effective amount of a therapeutic amount of a compound of the invention are also described.

L'invention concerne des procédés de traitement ou de prévention d'une maladie associée au peptide amyloïde chez un sujet, ce traitement consistant à administrer à ce dernier une quantité thérapeutique d'un composé selon l'invention. L'invention concerne également des procédés d'inhibition de l'épileptogenèse chez un sujet, consistant à administrer à ce dernier une quantité efficace d'un agent anti-épileptogène. Elle concerne aussi des procédés de traitement d'un sujet souffrant d'un état pathologique associé à l'épileptogenèse, consistant à administrer audit sujet une quantité efficace d'un agent anti-épileptogène. L'invention concerne en outre des procédés de traitement de convulsions chez un sujet, consistant à administrer à celui-ci une quantité thérapeutiquement efficace d'un composé selon l'invention.

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