Peptide inhibitors of toxins derived from ll-37

Details Peptide inhibitors of toxins derived from ll-37 Peptide inhibitors of toxins derived from ll-37

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61P 31/04 (2006.01) C07K 14/47 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2514584

The present invention relates to a group of peptidic compounds which have affinity for toxins and especially for bacterial toxins, such as lipopolysaccharide or lipoteichoic acid. These compounds can inhibit or neutralize the toxins. In addition, the present invention relates to the use of these compounds as therapeutic or diagnostic agents.

La présente invention concerne un groupe de composés peptidiques qui possèdent une affinité pour des toxines et en particulier pour des toxines bactériennes telles qu'un lipopolysaccharide ou qu'un acide lipoteichoïque. Ces composés peuvent inhiber ou neutraliser les toxines. De plus, cette invention concerne l'utilisation de ces composés comme agents thérapeutiques ou diagnostiques.

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