Preparation containing active ingredients and/or auxiliary...

A - Human Necessities – 61 – K

Patent

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A61K 9/70 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2387710

A preparation containing active substance(s) and optionally auxiliary substance(s) for the time- and/or dose-controllable release of said active substance(s), comprising a laminate of at least two layers, a matrix layer and a carrier layer, in rolled or folded shape, is characterized in that a) the matrix layer contains at least one active substance, is continuous at least in sections of itself, that at least one of the parameters thickness, width and concentration of the active substance or auxiliary substance of this layer is not constant, and b) in that the carrier layer is continuous and possesses a lower moisture permeability than the matrix layer.

L'invention concerne une préparation contenant un ou plusieurs principes actifs et/ou excipients, permettant de contrôler le temps de libération et la dose à libérer de ces principes actifs et/ou excipients. Cette préparation comprend au moins deux couches (1, 2) sous forme enroulée ou pliée. L'invention est caractérisée en ce que a) la première couche contient au moins un principe actif ou un excipient, elle est au moins partiellement continue, et au moins un des paramètres suivants : épaisseur, largeur et concentration du principe actif et de l'excipient de cette couche, n'est pas constant, et b) la deuxième couche est continue et possède un perméabilité à l'humidité inférieure à celle de la première couche.

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