Novel amino acid derivatives, method of producing them and...

Details Novel amino acid derivatives, method of producing them and... Novel amino acid derivatives, method of producing them and...

C - Chemistry, Metallurgy

07

K

C07K 5/06 (2006.01) A61K 31/47 (2006.01) A61K 38/05 (2006.01) C07D 215/38 (2006.01) C07D 401/14 (2006.01) C07D 491/04 (2006.01) C07D 491/056 (2006.01) C07K 5/02 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2182396

The invention concerns novel amino acid derivatives of general formula (I) and their pharmaceutically acceptable salts, in which the R2 group is (II) and R1, A, G, Y, Z and m have the meanings given in the description, and their production and use. The novel compounds are valuable neurokinin (tachykinin) antagonists.

L'invention concerne de nouveaux dérivés d'acides aminés et leurs sels ayant la formule générale (I), dans laquelle le groupe R?2¿ est représenté par (II) et R?1¿, A, G Y, Z et m ont la notation donnée dans la description, ainsi que leur préparation et leur utilisation. Ces nouveaux composés sont des antagonistes précieux de la neurokinine (tachykinine).

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