Substituted 1-naphthoylguanidines, process for their...

Details Substituted 1-naphthoylguanidines, process for their... Substituted 1-naphthoylguanidines, process for their...

C - Chemistry, Metallurgy

07

C

C07C 279/22 (2006.01) A61K 31/16 (2006.01) A61K 31/275 (2006.01) A61K 31/395 (2006.01) C07C 271/22 (2006.01) C07C 311/47 (2006.01) C07C 317/32 (2006.01) C07C 323/44 (2006.01) C07D 207/30 (2006.01) C07D 295/155 (2006.01)

Patent

CA 2206362

Substituted 1-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them. Substituted 1-naphthoylguanidines of the formula I see formula I in which R2 to R8 have the meanings indicated in the claims, are suitable as antiarrhythmic pharmaceuticals having a cardioprotective component for infarct prophylaxis and infarct treatment and for the treatment of angina pectoris. They also preventively inhibit the pathophysiological processes in the formation of ischemically induced damage, in particular in the production of ischemically induced cardiac arrhythmias.

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