C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/00 (2006.01) A61K 31/40 (2006.01) C07D 207/08 (2006.01) C07D 211/22 (2006.01) C07D 211/32 (2006.01) C07D 211/44 (2006.01) C07D 211/46 (2006.01)
Patent
CA 2505098
The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the beta-secretase enzyme is involved.
L'invention se rapporte à des composés qui sont des inhibiteurs de l'enzyme beta-secrétase et qui sont utiles dans le traitement ou dans la prévention de maladies dans laquelle l'enzyme beta-sécrétase est impliquée, telles que la maladie d'Alzheimer. L'invention se rapporte également à des compositions pharmaceutiques comprenant ces composés et à l'utilisation de ces composés et de ces compositions dans la prévention ou dans le traitement de ces maladies dans lesquelles l'enzyme béta-sécrétase est impliquée.
Coburn Craig A.
Stachel Shawn J.
Vacca Joseph P.
Merck & Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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