C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 249/08 (2006.01) C07D 521/00 (2006.01)
Patent
CA 2162773
The present invention provides an improved process for the production of triazoles of the formula: Image wherein Z is an optionally substituted (C6-C10)aryl group; R is a hydrogen atom, a (C1-C12)alkyl group, a (C3-C8) cydoalkyl group, a (C2-C8)alkenyl group, a (C5-C8) cydoalkenyl group, a (C2 to C8)alkenyl group, an optionally substituted (C7 to C14)aralkyl group, a (C2 to 4)alkynoxy group, an optionally substituted (C6 to C10)aryloxy group or a hydroxy group; Q is an optionally substituted 1-(1,2,4-triazolyl) or 4-(1,2,4-triazolyl); X is hydrogen or CN; m is zero or one; n is one or two the triazoles are provided in higher yields than previously obtained. The improved yields are obtained by the incremental or continuous addition of triazole salts to compounds having the formula: Image and m, n, R, X, Y, and Z are the same as defined above.
Gowling Lafleur Henderson Llp
Rohm And Haas Company
LandOfFree
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