Pre-fabricated corneal tissue lens and method of corneal...

A - Human Necessities – 61 – L

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A61L 27/36 (2006.01)

Patent

CA 2418306

This relates to a lens made of donor corneal tissue suitable for use as a contact lens or an implanted lens, to a method of preparing that lens, and to a technique of placing the lens on the eye. The lens is made of donor corneal tissue that is acellularized by removing native epithelium and keratocytes. These cells optionally are replaced with human epithelium and keratocytes to form a lens that has a structural anatomy similar to human cornea. The ocular lens may be used to correct conditions such as astigmatism, myopia, aphakia, and presbyopia.

Cette invention porte sur une lentille fabriquée dans le tissu cornéen d'un donneur qui est approprié pour être utilisé comme lentille de contact ou comme lentille implantée, et sur un procédé de préparation de cette lentille, ainsi que sur une technique de positionnement de la lentille sur l'oeil. La lentille est fabriquée dans le tissu cornéen d'un donneur qui est ascellularisé par retrait de l'épithélium natif et des kératocytes. Ces lentilles sont éventuellement remplacées par l'épithélium humain et les kératocytes de façon à former une lentille dont l'anatomie structurale est similaire à la cornée humaine. La lentille oculaire peut être utilisée pour corriger des états tels que l'astigmatisme, la myopie, l'aphaquie et la presbytie.

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