Flavanols and procyanidins promote homeostasis

G - Physics – 01 – N

Patent

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Details

G01N 33/48 (2006.01) A61K 31/352 (2006.01) A61K 31/353 (2006.01) A61K 31/7048 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2507704

The invention encompasses a screening method for identifying cytokine responsiveness of a human or a veterinary animal and products and assays for use therein comprising flavanols, procyanidins and/or derivatives thereof, or mixtures thereof, a method for diagnosing a cytokine phenotype in a human or a veterinary animal; methods for identifying a subject at risk of a condition associated with an inflammatory and/or immunomodulating pathway; methods for identifying a dietary and/or a pharmaceutical intervention to modulate a condition associated with an inflammatory and/or immunomodulating pathway; and the methods of prophylactic or therapeutic treatment of humans or veterinary animals with selected flavanols, procyanidins and/or derivatives thereof, or mixtures thereof.

L'invention concerne un procédé de criblage permettant d'identifier la capacité de réponse d'une cytokine chez un patient humain ou animal, ainsi que des produits et des systèmes de dosage pour ce procédé, comprenant des flavanols, des procyanidines et/ou des dérivés ou des mélanges de ceux-ci, un procédé permettant de diagnostiquer le phénotype d'une cytokine chez un patient humain ou animal, des procédés permettant d'identifier un sujet présentant un risque de souffrir d'une affection associée à un processus inflammatoire et/ou immunomodulateur, des procédés permettant d'identifier une mesure diététique et ou pharmaceutique permettant de moduler une affection associée à un processus inflammatoire et/ou immunomodulateur, et des méthodes permettant le traitement préventif ou curatif de patients humains ou animaux au moyen de flavanols, de procyanidines et/ou de dérivés ou de mélanges de ceux-ci.

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