Antithrombotic peptides derived from fibronectin type ii...

Details Antithrombotic peptides derived from fibronectin type ii... Antithrombotic peptides derived from fibronectin type ii...

C - Chemistry, Metallurgy

07

K

C07K 14/78 (2006.01) A61K 38/04 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2274142

Novel short peptides are disclosed which are selected from the group consisting of TAVTQTYGGNSNGEP and fragments thereof containing the minimal sequence TATQTY. These peptides are antithrombotic agents and mediate divalent cation-independent adhesion of platelets to fibronectin.

L'invention porte sur de nouveaux peptides courts choisis dans le groupe TAVTQTYGGNSNGEP et ses fragments, et présentant la séquence minimale TATQTY. Lesdits peptides sont des agents antithrombotiques induisant l'adhérence divalente des plaquettes, indépendante des cations, à la fibronectine.

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