Process for terminal hydroxylation of ethyl groups on...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/78 (2006.01) C12N 1/21 (2006.01) C12N 9/02 (2006.01) C12P 17/00 (2006.01) C12P 17/12 (2006.01)

Patent

CA 2062357

ABSTRACT OF THE DISCLOSURE A microbiological process is disclosed for terminal hydroxylation of ethyl groups substituted on aromatic 5- or 6-ring heterocycles. The hydroxylation is performed with microorganisms which: (a) contain the genes of a Pseudomonas OCT plasmid which form an active alkane monooxygenase, and (b) form no active chromosomal or plasmid-coded alcohol dehydrogenase.

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