Synthetic haemophilus influenzae conjugate vaccine

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/285 (2006.01) A61K 39/102 (2006.01) A61K 39/385 (2006.01) A61K 39/40 (2006.01) A61K 47/48 (2006.01) C07H 15/04 (2006.01) C07H 15/08 (2006.01) C07H 15/18 (2006.01) C07H 15/203 (2006.01) C07K 4/04 (2006.01) C07K 7/08 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2129101

Synthetic peptides have an amino acid sequence corresponding to at least one antigenic determinant of at least one protein, usually a structural protein, particularly the P1, P2 and P6 protein, of Haemophilus influenzae (Hi), particularly type b, and are used as is, in chimeric T-B form, in lipidated form, linked to a carrier molecule, particularly a synthetic PRP molecule and/or polymerized to form molecular aggregates, in vaccines against Hi.

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