Targeted enzymes comprising substrate recognition sites and...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/86 (2006.01) A61K 38/46 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01) A61P 43/00 (2006.01) C12N 15/52 (2006.01) C12N 15/82 (2006.01) C12N 9/50 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2431858

The present invention provides targeted enzymes that bind to targets better than the corresponding pre-targeted enzymes bind the target under like conditions, methods of making targeted enzymes, methods of using targeted enzymes to treat diseases, and pharmaceutical compositions comprising targeted enzymes.

La présente invention concerne des enzymes à cible qui se lient à des cibles mieux que les enzymes à cible prédéfinie correspondantes ne se lient à la cible dans des conditions analogues, des procédés permettant d'obtenir des enzymes à cible, des procédés d'utilisation d'enzymes à cible de manière à traiter des maladies et des compositions pharmaceutiques comprenant des enzymes à cible.

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