Outer membrane vesicle prime - protein boost vaccine

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/095 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2736151

The present invention provides a method of immunizing a subject against a disease caused by Neisseria meningitidis, comprising administering to the subject a primer composition comprising a meningococcal outer membrane vesicle preparation, and a booster composition comprising a meningococcal protein antigen preparation. Vaccine combinations comprising primer and booster compositions and associated uses are also provided.

La présente invention concerne un procédé dimmunisation dun sujet contre une maladie causée par Neisseria meningitidis, comprenant ladministration au sujet dune composition primaire comprenant une préparation de vésicules de membrane externe de méningocoque, et une composition de rappel comprenant une préparation dantigène de protéine de méningocoque. La présente invention concerne en outre des combinaisons de vaccin comprenant les compositions primaire et de rappel et les utilisations associées.

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