Procedure and methods for detecting alzheimer's disease

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2652258

This application concerns methods and compositions that can be used for detecting the Alzheimer disease in mammals, particularly in humans. It describes in particular serum markers for Alzheimer's disease and the way they are used for diagnostic procedures. It also concerns tools and/or kits that can be used for applying these procedures (reagents, probes, primers, antibodies, chips, cells, etc.) with the preparation thereof and the way to use them. The invention can be used to detect the presence or the progression of Alzheimer illness in mammals, including at early stages of the disease.

La présente demande concerne des méthodes et compositions utilisables pour la détection de la maladie d'Alzheimer chez les mammifères, en particulier les humains. Elle décrit notamment des marqueurs sériques de la maladie d'Alzheimer et leurs utilisations dans des méthodes de diagnostic. Elle concerne également des outils et/ou kits utilisables pour la mise en oeuvre de ces méthodes (réactifs, sondes, amorces, anticorps, puces, cellules, etc.), leur préparation et leurs utilisations. L'invention est utilisable pour détecter la présence ou l'évolution de la maladie d'Alzheimer chez les mammifères, y compris en phase précoce.

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