Thiazole derivatives as inhibitors of phosphatidylinositol...

C - Chemistry – Metallurgy – 07 – D

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C07D 417/14 (2006.01) A61K 31/4436 (2006.01) A61K 31/506 (2006.01) A61P 3/04 (2006.01) A61P 9/10 (2006.01) A61P 29/00 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2524401

Compounds of formula (I) in free or salt form, wherein R1, R2, R3, and R4 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.

La présente invention a trait à des composés de formule (I) sous forme libre ou de sel, dans laquelle : R?1¿, R?2¿, R?3¿, et R?4¿ sont tels que définis dans la description, utiles pour le traitement de conditions à médiation de la phosphatidylinositol 3-kinase. L'invention a également trait à des compositions pharmaceutiques contenant les composés et un procédé pour la préparation des composés.

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