Vegfr3 inhibitors

Details Vegfr3 inhibitors Vegfr3 inhibitors

A - Human Necessities

61

K

A61K 31/529 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2664148

The present invention relates to the use of some of the macrocyclic quinazoline derivatives described in PCT publication WO2004/105765 as inhibitors of VEGFR3 mediated biological activities, especially those activities which are mediated by VEGFR3 ligands VEGF-C and/or VEGF-D.

La présente invention porte sur l'utilisation de certains des dérivés de la quinazoline macrocyclique décrits dans la publication de la demande internationale PCT WO2004/105765 en tant qu'inhibiteurs d'activités biologiques à médiation par VEGFR3, notamment les activités qui sont à médiation par les ligands de VEGFR3, VEGF-C et/ou VEGF-D.

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