Cyclopentane and cyclopentene derivatives with antiallergic...

Details Cyclopentane and cyclopentene derivatives with antiallergic... Cyclopentane and cyclopentene derivatives with antiallergic...

C - Chemistry, Metallurgy

07

C

C07C 62/34 (2006.01) A61K 31/00 (2006.01) C07C 45/62 (2006.01) C07C 45/68 (2006.01) C07C 45/70 (2006.01) C07C 49/753 (2006.01) C07C 62/12 (2006.01) C07C 69/734 (2006.01) C07C 69/757 (2006.01) C07C 217/52 (2006.01) C07C 217/74 (2006.01) C07C 229/48 (2006.01) C07C 233/23 (2006.01) C07C 235/40 (2006.01) C07C 251/44 (2006.01) C07C 255/46 (2006.01) C07C 311/59 (2006.01) C07D 213/40 (2006.01) C07D 235/02 (2006.01) C07D 257/04 (2006.01)

Patent

CA 2120351

2120351 9307111 PCTABS00021 Compounds illustrated by general formula (I) useful as PDE IV inhibitors and for inhibiting the production of Tumor Necrosis Factor (TNF) are disclosed herein. In formula (I) R1 is C1-12 alkyl unsubstituted or substituted by 1 or more halogens; C3-6 cyclic alkyl unsubstituted or substituted by 1 to 3 methyl groups or one ethyl group; C4-6 cycloalkyl containing one or two unsaturated bonds; C7-11 polycycloalkyl, -(CR14R14)nC(O)-O-(CR14R14)m-R10, -(CR14R14)nC(O)-O-(CR14R14)r-R11, -(CR14R14)xOH, -(CR14R14)sO(CR14R14)m-R10, -(CR14R14)sO(CR14R14)r-R11, -(CR14R14)n-(C(O)NR14)-(CR14R14)m-R10, -(CR14R14)n-(C(O)NR14)-(CR14R14)r-R11, -(CR14R14)y-R11 or -(CR14R14)z-R10; X2 is O or NR14; X3 is hydrogen or X; X is YR2, halogen, nitro, NR14R14 or formamide; Y is O or S(O)m; R2 is -CH3 or -CH2CH3, each may be unsubstituted or substituted by 1 to 5 fluorines; A is (a), (b), (c), (d) or (e); B is >C=Z or C=S.

Affiliated with

Also associated with

Rating

Cyclopentane and cyclopentene derivatives with antiallergic... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cyclopentane and cyclopentene derivatives with antiallergic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclopentane and cyclopentene derivatives with antiallergic... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1617309