Novel 2-azetidinone derivatives as cholesterol absorption...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 405/12 (2006.01) A61K 31/397 (2006.01) A61P 3/06 (2006.01) A61P 9/10 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2609993

Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.

L~invention concerne des composés de formule (I) : (où des groupes variables sont tels que définis dans la présente) des sels, solvates, des solvates de ces sels et des promédicaments pharmaceutiquement acceptables de ceux-ci et leur utilisation en tant qu~inhibiteurs de l'absorption du cholestérol pour le traitement de l'hyperlipidémie. Des méthodes pour leur préparation et des compositions pharmaceutiques qui les contiennent sont aussi décrites.

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