Human tumor necrosis factor delta and epsilon

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/28 (2006.01) A61K 31/70 (2006.01) A61K 38/19 (2006.01) A61K 48/00 (2006.01) C07K 14/525 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2247285

The invention relates to human TNF delta and TNF epsilon polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides, polypeptides, agonists and antagonists for applications, which relate, in part, to research, diagnostic and clinical arts.

Cette invention concerne des polypeptides de facteurs de nécrose tumorale delta et epsilon chez l'homme, des polynucléotides codant ces polypeptides, des procédés de production de ces polypeptides notamment par l'expression des polynucléotides, ainsi que des agonistes et des antagonistes de ces polypeptides. Cette invention concerne également des procédés d'utilisation de ces polynucléotides, polypeptides, agonistes et antagonistes dans des applications qui ont partiellement trait aux domaines diagnostique, clinique et de la recherche.

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