Natively glycosylated mammalian biological molecules...

Details Natively glycosylated mammalian biological molecules... Natively glycosylated mammalian biological molecules...

C - Chemistry, Metallurgy

07

K

C07K 14/435 (2006.01) C07K 14/475 (2006.01) C07K 14/52 (2006.01) C12N 5/00 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2613600

The disclosure describes a method for producing natively glycosylated mammalian biological molecules by electromagnetically stimulating mammalian cells using an electromagnetic field. The mammalian cells can be grown in a cell culture chamber, and preferably in a bioreactor that is exposed to a time varying electromagnetic force. The biological molecules can be isolated from the cells and used for therapeutic, research, or other purposes.

L'invention concerne une méthode de production de molécules biologiques mammaliennes à glycosylation naturelle par une stimulation électromagnétique de cellules mammaliennes faisant intervenir un champ magnétique. Les cellules mammaliennes peuvent être cultivées dans une chambre de culture cellulaire et, de préférence, dans un bioréacteur soumis à une force électromagnétique variant dans le temps. Les molécules biologiques peuvent être isolées des cellules et utilisées à des fins thérapeutiques, expérimentales ou autres.

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