Oxirancarboxylic acids for the treatment of diabetes

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

IPC codes

C07D 303/48 (2006.01) A61K 31/335 (2006.01)

Type

Patent

Patent number

CA 2280960

Description

The invention relates to novel arylalkyl- or aryloxyalkyl-substituted oxiranecarboxylic acids of the general formula I (see formula I) in which Ar, R3, Y and n are as defined in the description, and also to medicaments comprising them and to their use for the treatment and prophylaxis of the disorders mentioned in Claim 4 which are caused by disturbances of glucose and/or lipid metabolism, such as, for example, diabetes type 2 and other insulin-resistant conditions.

L'invention concerne de nouveaux acides carboxyliques d'oxirane substitués par arylalkyle ou aryloxyalkyle de la formule générale (I) dans laquelle Ar, R<3>, Y et n ont les significations mentionnées dans la description. L'invention concerne également des médicaments contenant lesdits acides et leur utilisation pour traiter et assurer la prophylaxie des maladies mentionnées dans la revendication 3, qui reposent sur des troubles du métabolisme glucosique et/ou lipidique, tels que le diabète de type 2 et d'autres états de résistance insulinique.

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