Sodium salt of an azo derivative of 5-aminosalicylic acid

Details Sodium salt of an azo derivative of 5-aminosalicylic acid Sodium salt of an azo derivative of 5-aminosalicylic acid

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/435 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01)

Patent

CA 2405741

The present invention relates to the sodium salt of (Z)-2-hydroxy-5-[[4-3-[4-[2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)methyl]-1- piperidinyl]-3--oxo-1-phenyl-1-propenyl]phenyl]azo]benzoic acid, whose formula is shown below, as well as to the pharmaceutical compositions containing it, to a procedure for its preparation and to its use for the manufacture of medicaments for the treatment or prevention of inflammatory bowel disease.

L'invention concerne un sel de sodium de l'acide (Z)-2-hydroxy-5-[[4-[3-[4-[(2-méthyl-1H-imidazo[4,5-c]pyridin-1-yl)méthyl]-1-pipéridinyl]-3-oxo-1-phényl-1-propényl]phényl]azo]benzoïque ainsi que des compositions pharmaceutiques le contenant, une procédure de préparation et son utilisation dans la fabrication de médicaments pour le traitement ou la prévention de l'affection intestinale inflammatoire.

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