Phenoxy substituted benzocondensed heteroaryl derivatives as...

C - Chemistry – Metallurgy – 07 – D

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C07D 307/79 (2006.01) A61K 31/343 (2006.01) A61K 31/4184 (2006.01) A61P 5/14 (2006.01) A61P 9/06 (2006.01) A61P 17/00 (2006.01) C07D 235/06 (2006.01)

Patent

CA 2435820

This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac and metabolic disorders, such as cardiac arrhythmias, thyrotoxicosis, subcllinical hyperthyrodism and liver diseases.

L'invention concerne de nouveaux composés qui sont des ligands de récepteurs thyroïdiens, de préférence antagonistes, et des méthodes d'utilisation de ces composés pour le traitement de troubles cardiaques et métaboliques tels que les arythmies cardiaques, les thyréotoxicoses, les hyperthyroïdies subcliniques et les maladies hépatiques.

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