Stable ophthalmic formulation containing an antibiotic and a...

Details Stable ophthalmic formulation containing an antibiotic and a... Stable ophthalmic formulation containing an antibiotic and a...

A - Human Necessities

61

K

A61K 9/08 (2006.01) A61K 31/4709 (2006.01) A61K 31/573 (2006.01) A61K 31/7036 (2006.01) A61K 47/40 (2006.01)

Patent

CA 2516429

The present invention provides a clear stable ophthalmic composition comprising (a) a quinolone or an aminoglycoside, (b) a corticosteroid, (c) a cyclodextrin and (d) other pharmaceutically acceptable excipients in a liquid vehicle.

La présente invention se rapporte à une composition ophtalmique stable transparente, qui contient : (a) un agent anti-infectieux ; (b) un agent anti-inflammatoire stéroïdique ; (c) un agent complexant pouvant former un complexe d'insertion, et (d) d'autres excipients pharmaceutiquement acceptables contenus dans un véhicule liquide. La composition selon l'invention se caractérise en ce qu'elle est exempte de tout autre polymère favorisant la complexation, et que, lorsqu'elle est conservée à température ambiante pendant un an, elle ne présente pas de précipitation durant la période de conservation.

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