C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/42 (2006.01) A01K 67/027 (2006.01) A61K 39/395 (2006.01) A61P 19/02 (2006.01) C07K 14/435 (2006.01) C07K 16/00 (2006.01) C12Q 1/37 (2006.01) G01N 33/564 (2006.01)
Patent
CA 2696011
The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG breakdown products retaining antigen binding but having lost effector functions.
Cette invention a trait à des compositions d'anticorps et à l'utilisation de ces compositions pour détecter des processus pathologiques associés avec l'élaboration de protéases. Les réactifs sont orientés de manière à évaluer le produit de décomposition des IgG qui est le résultat de ce clivage protéolytique. L'invention concerne par ailleurs l'utilisation d'un composé thérapeutique immunospécifique des produits de décomposition des IgG conservant la fonction de fixation antigénique mais dépourvu des fonctions effectrices.
Jordan Robert
Petrone Diane D.
Ryan Mary
Centocor Ortho Biotech Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
LandOfFree
Immunoglobulin cleavage fragments as disease indicators and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Immunoglobulin cleavage fragments as disease indicators and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunoglobulin cleavage fragments as disease indicators and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1623053