Process for selective reduction

Details Process for selective reduction Process for selective reduction

C - Chemistry, Metallurgy

07

D

C07D 307/33 (2006.01) C07B 53/00 (2006.01) C07D 307/22 (2006.01) C07D 307/30 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2313906

Process for the stereoselective reduction of chiral .alpha.- or .beta.-keto esters which have a chiral centre in the .gamma. position in an inert solvent at temperatures from -80 to +50°C using a reductant obtained by reaction of NaBH4 and (D)- or (L)-tartaric acid, to give the corresponding diastereomeric hydroxy compounds in each case.

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