Carbamic acid derivatives and method for preparing the same

C - Chemistry – Metallurgy – 07 – D

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C07D 401/04 (2006.01) A61K 31/445 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) C07D 211/36 (2006.01) C07D 211/60 (2006.01) C07D 401/14 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2060393

Anti-dementia medicaments comprising a carbamic acid derivatives or a phamaceutically acceptable acid addition salt thereof having anti-amnesic activity are provided. The carbainic acid derivatives are represented by the general formula (1) (see formula I) wherein Ar denotes an aromatic heterocyclic ring or its benzene-condensed ring, which may have at least one substituent, or a phenyl group which may have at least one substituent, R1 denotes a hydrogen atom or a lower alkyl group, R2 denotes a lower alkyl group which may be substituted with a halogen atom, a phenyl group which may have at least one substituent, a naphthyl group, or a five- or six-membered heterocyclic ring and its benzene-condensed ring; X and Y, which may be the same or different, each denote a sulfur atom or an oxygen atom.

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