Methods of using pde v inhibitors for the treatment of...

Details Methods of using pde v inhibitors for the treatment of... Methods of using pde v inhibitors for the treatment of...

A - Human Necessities

61

K

A61K 31/522 (2006.01) A61K 31/422 (2006.01) A61P 9/04 (2006.01)

Patent

CA 2587499

The uses of PDE V inhibitors in methods for the treatment of congestive heart failure and other physiological disorders, as a monotherapy and in combination with other active agents are disclosed. Such PDE V inhibitors include those having the formula (I), with the variables defined herein: (I) For example, a representative compound useful in the methods of the invention is: (II)

L'invention concerne des méthodes d'utilisation d'inhibiteurs de PDE de type V dans des méthodes pour traiter une insuffisance cardiaque congestive et d'autres troubles physiologiques, en tant que monothérapie et combinées à d'autres principes actifs. De tels inhibiteurs de PDE type V comprennent des inhibiteurs de formule (I) dont les variables sont définies dans la description. Par exemple, un composé représentatif utile des méthodes de l'invention est désigné par la formule (II).

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