Methods for modeling, predicting, and optimizing high...

Details Methods for modeling, predicting, and optimizing high... Methods for modeling, predicting, and optimizing high...

G - Physics

01

N

G01N 30/86 (2006.01)

Patent

CA 2402155

A method for modeling high performance liquid chromatography parameters is disclosed. The method can predict retention times, peak widths, and resolution. The method can also perform a multivariate optimization of a separation over two or more user-adjustable parameters. The method can be applied to isocratic and gradient separations and any combination of isocratic and gradient conditions.

L'invention concerne un procédé de modélisation des paramètres en chromatographie liquide haute performance, qui permet de prévoir les temps de rétention, les largeurs de crête et la résolution. Ce procédé permet également d'effectuer une optimisation à plusieurs variables de séparation sur deux ou plus de deux paramètres pouvant être ajustés par l'utilisateur. Il est possible d'appliquer le procédé à des séparations isocratiques et par gradient et à toute combinaison de conditions isocratiques et par gradient.

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