Pyrrolidine, piperidine and piperazine derivatives and...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 417/04 (2006.01) A61K 31/4355 (2006.01) A61K 31/437 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) A61P 3/10 (2006.01) C07D 271/113 (2006.01) C07D 285/135 (2006.01) C07D 417/14 (2006.01) C07D 471/10 (2006.01) C07D 487/04 (2006.01) C07D 487/08 (2006.01) C07D 491/107 (2006.01)

Patent

CA 2739490

The present invention relates to novel Pyrrolidine, Piperidine and Piperazine Derivatives, pharmaceutical compositions comprising the Pyrrolidine, Piperidine and Piperazine Derivatives and the use of these compounds for treating or preventing treating allergy, an allergy-induced airway response, congestion, a cardiovascular disease, an inflammatory disease, a gastrointestinal disorder, a neurological disoder, a metabolic disorder, obesity, an obesity-related disorder, diabetes, a diabetic complication, impaired glucose tolerance or impaired fasting glucose.

La présente invention concerne de nouveaux dérivés de pyrrolidine, de pipéridine et de pipérazine, des compositions pharmaceutiques contenant ces dérivés, et l'utilisation de ces composés pour prévenir ou traiter une allergie, une réaction des voies aériennes induite par une allergie, une congestion, une maladie cardiovasculaire, une maladie inflammatoire, une affection gastro-intestinale, une affection neurologique, un trouble métabolique, l'obésité ou une affection associée à l'obésité, le diabète, une complication diabétique, l'intolérance au glucose ou l'hyperglycémie modérée à jeun.

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