Insecticidal polypeptides and methods of use thereof

C - Chemistry – Metallurgy – 07 – K

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C07K 14/435 (2006.01) C12N 15/12 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2595757

A family of insecticidal polypeptides expressed in the venom gland of spiders of the genera Atrax and Hadronyche have been described. Also includes are polynucleotides and expression vectors encoding the polypeptides and insect viruses and cells expressing the polypeptides. Transgenic plants and insects expressing the insecticidal polypeptides are also described. The insecticidal polypeptides may be employed in methods and compositions for treating insects, insect larvae, and plants.

L'invention concerne une famille de polypeptides insecticides exprimés dans la glande à venin d'araignées des genres Atrax et Hadronyche. L'invention concerne également des polynucléotides et des vecteurs d'expression codant lesdits polypeptides et des virus d'insectes, ainsi que des cellules exprimant ces polypeptides. L'invention concerne encore des insectes et des plantes transgéniques exprimant ces polypeptides insecticides. Les polypeptides insecticides selon l'invention peuvent être utilisés dans des procédés et des compositions de traitement d'insectes, de larves d'insectes et de plantes.

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