Substituted imidazoles as bombesin receptor subtype-3...

Details Substituted imidazoles as bombesin receptor subtype-3... Substituted imidazoles as bombesin receptor subtype-3...

C - Chemistry, Metallurgy

07

D

C07D 401/10 (2006.01) A61K 31/4178 (2006.01) A61K 31/4439 (2006.01) A61P 3/10 (2006.01) C07D 403/10 (2006.01)

Patent

CA 2664794

Certain novel substituted imidazoles are ligands of the human bombesin receptor and, in particular, are selective ligands of the human bombesin receptor subtype-3 (BRS-3). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of BRS-3, such as obesity, and diabetes.

L'invention concerne certains nouveaux imidazoles substitués qui sont des ligands du récepteur de la bombésine humaine et, en particulier, des ligands sélectifs du sous-type 3 du récepteur de la bombésine humain (BRS-3). Lesdits imidazoles substitués sont utiles dans le traitement, le contrôle et la prévention de maladies et de troubles réagissant à la modulation du BRS-3, comme l'obésité et le diabète.

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