Gmg-3, gmg-4, and gmg-6 polynucleotides and polypeptides and...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/435 (2006.01) A61K 38/04 (2006.01) C07K 14/47 (2006.01) C12N 15/11 (2006.01) C12N 15/63 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2433841

The present invention relates to the field of metabolic research. Metabolic disorders, such as obesity, are a public health problem that is serious and widespread. GMG-3, GMG-4, Cluster 1, GMG-6A, or GMG-6B polypeptides have been identified that are beneficial in the treatment of metabolic disorders. These compounds should be effective for reducing body mass and for treating metabolic-related diseases and disorders. These metabolic-related diseases and disorders include hyperlipidemias, atherosclerosis, diabetes, and hypertension.

La présente invention concerne le domaine de la recherche métabolique. Des troubles métaboliques, tels que l'obésité, constituent un problème de santé publique grave et étendu. On a identifié des polypeptides GMG-3, GMG-4, groupe 1, GMG-6A, ou GMG-6B qui sont bénéfiques dans le traitement de troubles métaboliques. Ces composés devraient permettre de réduire la masse corporelle et de traiter les maladies et les troubles liés au métabolisme. Ces maladies et troubles liés au métabolisme comprennent les hyperlipidémies, l'athérosclérose, le diabète et l'hypertension.

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