Inducing cellular immune responses to carcinoembryonic...

Details Inducing cellular immune responses to carcinoembryonic... Inducing cellular immune responses to carcinoembryonic...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/04 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 4/12 (2006.01) C07K 7/00 (2006.01) C07K 9/00 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2392764

This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare carcino-embryonic antigen (CEA) epitopes, and to develop epitope-based vaccines directed towards CEA-bearing tumors. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of cancer.

L'invention fait appel à nos connaissances des mécanismes par lesquels un antigène est reconnu par des lymphocytes T, pour identifier et préparer des épitopes de l'antigène carcinoembryonnaire (ACE) et pour mettre au point des vaccins sur la base de ces épitopes dirigés contre les tumeurs contenant des ACE. Plus précisément, cette demande concerne la découverte de compositions pharmaceutiques et leurs méthodes d'utilisation dans la prévention et le traitement du cancer.

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