Heterocyclic inhibitors of 11-.beta. hydroxyl steroid...

Details Heterocyclic inhibitors of 11-.beta. hydroxyl steroid... Heterocyclic inhibitors of 11-.beta. hydroxyl steroid...

C - Chemistry, Metallurgy

07

D

C07D 405/04 (2006.01) A61K 31/454 (2006.01) A61K 31/5377 (2006.01) C07D 249/08 (2006.01)

Patent

CA 2652375

The present invention relates to inhibitors of 11 -beta hydroxyl steroid dehydrogenase type 1 such as: (Formula) and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11 -beta hydroxyl steroid dehydrogenase type 1.

La présente invention concerne des inhibiteurs hétérocycliques de la déshydrogénase du stéroïde hydroxyle 11-B de type 1 et des compositions pharmaceutiques à base de ceux-ci. Les composés selon l'invention peuvent être utiles dans le traitement de diverses maladies associées à l'expression ou l'activité de la déshydrogénase du stéroïde hydroxyle 11-B de type 1.

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