Polynucleotides encoding antigenic hiv type b and/or type c...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/74 (2006.01) A61K 39/21 (2006.01) C07H 21/04 (2006.01) C07K 14/16 (2006.01) C12N 15/867 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2452119

The present invention relates to polynucleotides encoding immunogenic HIV polypeptides. Uses of the polynucleotides in applications including immunization, generation of packaging cell lines, and production of HIV polypeptides are also described. Polynucleotides encoding antigenic HIV polypeptides are described, as are uses of these polynucleotides and polypeptide products therefrom, including formulations of immunogenic compositions and uses thereof.

La présente invention a trait à des polynucléotides codant pour des polypeptides immunogènes du VIH. L'invention concerne également les utilisations de ces polynucléotides dans des applications parmi lesquelles figurent l'immunisation, la génération de lignées d'encapsidation et la production de polypeptides du VIH. L'invention se rapporte par ailleurs à des polynucléotides codant pour des polypeptides antigéniques du VIH, ainsi qu'à l'utilisation de ces polynucléotides et des produits polypeptidiques en résultant. L'invention concerne en outre des formulations de compositions immunogènes ainsi que leurs utilisations.

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