Anti-malignant tumor agent used in malignant neoplasms...

Details Anti-malignant tumor agent used in malignant neoplasms... Anti-malignant tumor agent used in malignant neoplasms...

A - Human Necessities

61

K

A61K 31/765 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2325667

The anti-malignant tumor agent of the present invention comprises a mixture of poly L-lactates that are cyclic and linear oligomers having degrees of condensation of 3 to 23, which is prepared by dehydration condensation of L-lactic acid in a nitrogen atmosphere under stepwise reduced pressure and at an increasing temperature, drying ethanol- and methanol-soluble components in the resulting reaction solution under reduced pressure, subjecting the product to chromatography on a reverse phase ODS column, and after elution with 25 to 50 % aqueous acetonitrile at pH 2.0, eluting said mixture of poly L-lactates with 100 % acetonitrile at pH 2Ø

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