Method for making very fine particles consisting of a...

Details Method for making very fine particles consisting of a... Method for making very fine particles consisting of a...

A - Human Necessities

61

K

A61K 47/48 (2006.01)

Patent

CA 2426697

The invention concerns a method for making very fine particles containing at least an active principle inserted in a host molecule and a device for implementing said method. The method is characterised in that it consists in forming a solution of the active principle in a first liquid solvent and of a product formed by the host molecules in a second liquid solvent, then in contacting the resulting solutions with a supercritical pressure fluid, so as to precipitate the host molecules which are dissolved therein.

La présente invention concerne un procédé de fabrication de très fines particules contenant au moins un principe actif inséré dans une molecule hôte ainsi qu'un dispositif permettant la mise en oeuvre de ce procédé. Suivant le procédé on met en solution le principe actif dans un premier solvant liquide et un produit formé des molécules hôtes dans un second solvant liquide, on fait ensuite en sorte d'assurer une mise en contact des solutions formées avec un fluide à pression supercritique, de façon à faire précipiter les molécules hôtes qui y sont dissoutes.

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