Methods for treating mild cognitive impairment

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/57 (2006.01) A61K 31/00 (2006.01) A61K 31/567 (2006.01)

Patent

CA 2389570

This invention generally pertains to the field of psychiatry. In particular, this invention pertains to the discovery that agents which inhibit the binding of cortisol to its receptors can be used in methods for treating mild cognitive impairment. Mifepristone, a potent specific glucocorticoid receptor antagonist, can be used in these methods. The invention also provides a kit for treating mild cognitive impairment in a human including a glucocorticoid receptor antagonist and instructional material teaching the indications, dosage and schedule of administration of the glucocorticoid receptor antagonist.

D'une manière générale, l'invention concerne le domaine de la psychiatrie. D'une manière plus spécifique, l'invention concerne la découverte selon laquelle des agents inhibant la liaison du cortisol à ses récepteurs peuvent être utilisés dans des méthodes permettant de traiter une déficience intellectuelle légère. La mifepristone, un puissant antagoniste des récepteurs des glucocorticoïdes spécifiques, peut être utilisée dans ces méthodes. L'invention concerne également des trousses permettant de traiter une déficience intellectuelle légère chez un être humain, cette trousse comprenant un antagoniste des récepteurs des glucocorticoïdes et du matériel didactique comportant les indications, le dosage et le programme d'administration de l'antagoniste des récepteurs des glucocorticoïdes.

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