Optically active 8-methoxyouinolonecarboxylic acid...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/10 (2006.01) A61K 31/47 (2006.01) C07C 31/36 (2006.01) C07C 271/16 (2006.01) C07D 207/10 (2006.01) C07D 207/12 (2006.01) C07D 207/14 (2006.01) C07D 309/12 (2006.01) C07D 401/04 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2036516

ABSTRACT OF THE DISCLOSURE Optically active 8-methoxyquinolonecarboxylic acids repsesented by the formula (I) Image (I) wherein R1 is lower alkyl have been found to possess potent antibacterial activity against both Gram-negative and Gram- positive bacteria. The compounds may be synthesized from novel optically active intermediates.

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