Polyethylene or polypropylene glycol containing polymer

C - Chemistry – Metallurgy – 08 – F

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C08F 283/06 (2006.01) C07H 21/00 (2006.01) C07K 1/04 (2006.01) C07K 17/08 (2006.01) C08F 290/06 (2006.01) C12P 19/00 (2006.01) G01N 30/48 (1990.01)

Patent

CA 2129442

A crosslinked polyethylene or polypropylene glycol containing polymer which has a unique spatial structure and can be designed especially for application as a chromatographic resin or as a solid support for the synthesis of peptides, oligonucleo- tides or oligosaccharides or as a substrate for the immobilization of proteins. The polymer is formed by radical copolymerization of derivatized polyethylene glycol or polypropylene glycol bis-end substituted with a moiety selected from the group consisting of acryloylalkyl, acryloylaryl, acrylamidoalkyl and acrylamidoaryl with an acrylic amide, nitrile or ester. When it is to be used as a solid support or immobilization substrate, the polymer will incorporate a spacer comprising functional groups for the attachment of peptides, proteins, nucleotides or saccharides such as those selected from the group consisting of amino, alkylamino, hydroxy, carboxyl, mercapto, sulfeno, sulfino, sulfo and derivatives thereof.

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