Method to improve the efficacy of therapeutic radiolabeled...

Details Method to improve the efficacy of therapeutic radiolabeled... Method to improve the efficacy of therapeutic radiolabeled...

A - Human Necessities

61

K

A61K 41/00 (2006.01) A61K 51/10 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2546057

Disclosed are radiolabeled drugs and methods to improve their efficacy by using a radiosensitizer such that the radiosensitizer is either part of the radiolabeled drug by directly attaching the radiosensitizer to the radiolabeled drug or by producing a mixture of the radiolabeled drug and an analogue of the drug with the radiosensitizer attached to the drug instead of the radiolabel.

L'invention concerne des médicaments radiomarqués et des procédés permettant d'améliorer leur efficacité au moyen d'un agent de radiosensibilisation. Selon ces procédés, soit l'agent de radiosensibilisation fait partie du médicament radiomarqué en étant directement lié à ce dernier, soit un mélange dudit médicament radiomarqué et d'un analogue de ce dernier est produit et l'agent de radiosensibilisation est lié au médicament au lieu de l'agent radiomarqueur.

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