Oligomer-tricyclic conjugates

Details Oligomer-tricyclic conjugates Oligomer-tricyclic conjugates

A - Human Necessities

61

K

A61K 47/48 (2006.01)

Patent

CA 2704836

The invention provides small molecule drugs that are chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the small molecule drug not attached to the water soluble oligomer.

La présente invention concerne des médicaments à petites molécules qui sont chimiquement modifiés par une liaison covalente avec un oligomère hydrosoluble. Selon l'invention, un conjugué présente des caractéristiques qui sont différentes des caractéristiques du médicament à petites molécules non lié à l'oligomère hydrosoluble lorsque ledit conjugué est administré selon l'une des voies d'administration possibles.

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