Chiral 3-halophthalic acid derivatives

Details Chiral 3-halophthalic acid derivatives Chiral 3-halophthalic acid derivatives

C - Chemistry, Metallurgy

07

C

C07C 319/20 (2006.01) C07C 315/02 (2006.01) C07C 317/28 (2006.01) C07C 323/42 (2006.01)

Patent

CA 2577942

The invention relates to novel salts of chiral 3-halophthalic acid derivatives of formula (I) from 3-halophthalic acid anhydrides of formula (II), amines of formula (III), a method for the production thereof, the use thereof for producing chiral phthalic acid diamides of formula (V), and a novel method for producing chiral phthalic acid diamides of formula (V). According to the invention, salts of chiral 3-halophthalic acid derivatives of formula (I) are transformed into the corresponding isophthalamides of formula (VI), which are reacted with arylamine of formula (VII).

L'invention concerne de nouveaux sels de dérivés chiraux d'acide 3-halophtalique de formule (I) à partir d'anhydrides 3-halophtaliques de formule (II) et des amines de formule (III), un procédé de production associé, leur utilisation pour réaliser des phtalamides chiraux de formule (V) ainsi qu'un nouveau procédé pour produire des phtalamides chiraux de formule (V), selon lequel des sels de dérivés chiraux d'acide 3-halophtalique de formule (I) sont transformés en isophtalimides correspondants de formule (VI), lesquels sont mis à réagir avec des arylamines de formule (VII).

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