C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/38 (2006.01) A61K 31/4709 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2532452
Compounds of formula (I) and pharmaceutically acceptable salts thereof are provided: wherein R1, m, X, R2, n, W, p, Y, Z, R3, R4, R5 and q have the meanings as defined in the description. Methods of preparation and uses thereof in therapy, particularly for CNS disorders such as depression or anxiety, are also disclosed.
L'invention concerne des composés correspondant à la formule (I) et des sels pharmaceutiquement acceptables de ceux-ci. Dans ladite formule (I), R¿1?, m, X, R¿2?, n, W, p, Y, Z, R¿3?, R¿4?, R¿5? et q correspondent aux définitions données dans la description. L'invention concerne également des procédés de préparation et les utilisations de ces composés en thérapie, en particulier pour le traitement de troubles du système nerveux central tels que la dépression ou l'anxiété.
Bergauer Markus
Bertani Barbara
Biagetti Matteo
Bromidge Steven Mark
Falchi Alessandro
Glaxo Group Limited
Gowling Lafleur Henderson Llp
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