Method and composition for prevention of scar formation in...

Details Method and composition for prevention of scar formation in... Method and composition for prevention of scar formation in...

A - Human Necessities

61

K

A61K 31/5575 (2006.01)

Patent

CA 2363131

A method comprising the use of a prostaglandin of subtype A or J for the prevention of scar formation in the filtration bleb and drainage fistula after glaucoma surgery is described. Compositions containing a prostaglandin of subtype A or J can be used topically on the eye, either as ointments or drug inserts, for various time periods after surgery to avoid fibroblast activity and proliferation in the filtration bleb end drainage fistula.

L'invention concerne une méthode consistant en l'utilisation d'une prostaglandine de sous-type A ou J dans la prévention de la formation de cicatrices dans la bulle de filtration et une fistule de drainage après une chirurgie du glaucome. On peut utiliser des compositions contenant une prostaglandine de sous-type A ou J localement sur l'oeil, soit sous la forme d'onguents soit sous la forme de médicaments insérés, pendant diverses durées après une chirurgie, afin d'éviter une activité fibroblastique et une prolifération dans la bulle de filtration et la fistule de drainage.

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