Genetically modified t cells

Details Genetically modified t cells Genetically modified t cells

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) A61K 35/14 (2006.01) A61K 35/18 (2006.01) A61K 48/00 (2006.01) C12N 15/09 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2198891

The invention concerns genetically altered mature T-cells with autoreactive receptors which carry in their genome at least one externally introduced gene which can express a (poly)peptide. The invention further concerns drugs containing such T-cells.

L'invention concerne des lymphocytes T matures modifiés génétiquement, contenant des récepteurs autoréactifs et comportant dans leur génome au moins un gène, introduit de l'extérieur, pouvant exprimer un (poly)peptide. L'invention concerne en outre des médicaments contenant ces lymphocytes T.

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